It is not the first time that studies have been published that link coffee intake with longevity, but now it seems that a mechanism underlying this link has been found. At least that’s what researchers at the Institute for Immunity, Transplantation and Infection at Stanford University in California say. The study has been published in the journal Nature Medicine.
The anti-inflammatory properties of caffeine
Apparently, caffeine (coffee, tea, chocolate …) has anti-inflammatory properties, which would increase the lives of people, because there is an inflammatory process that could promote the development of cardiovascular diseases in adult life.
For this conclusion, led by Mark Davis, leader of the work, first identified the inflammatory processes that could contribute to poor heart health in old age.
Next, the medical history of each of the older participants in the study was examined. Subsequent research revealed that older participants who had high activity of a group of genes were also significantly more likely to have arterial stiffness, a risk factor for heart attack and stroke. But what they also found is that they were more likely to find caffeine metabolites in the blood of older adults with low activity of these gene groups.
By incubating immune cells with the metabolites of caffeine and nucleic acid metabolites, they discovered that the metabolites of caffeine prevented the inflammatory effects of nucleic acid metabolites. As Davis points out:
That something that many people drink, and really like to drink, could have a direct benefit came as a surprise to us. What we have shown is a correlation between caffeine consumption and longevity. And we have demonstrated more rigorously, in laboratory tests, a very plausible mechanism to explain why this might be so.
We must remember that coffee is one of the most consumed beverages in the world and also one of the most exported products in the world. In Spain alone, 22 million people consume at least one cup of coffee per day. And that all these are the most unusual substances that are in your coffee cup